The Wilkinson Lab studies sensory plasticity. Muscles contain neurons which sense muscle length and movement and are the main contributors to the sense of body position and movement, or proprioception. Alterations to these sensory neurons can lead to movement and balance problems. We are currently studying the effect of inflammation and obesity on muscle proprioceptor activity. To learn more about our research, check out our latest papers:
S-H. Woo, V. Lukacs, J.C. de Nooij, D. Zaytseva#, C.R. Criddle#, A. Francisco, T.M. Jessell, K.A. Wilkinson, A. Patapoutian (2015) Piezo2 is the principal mechanotransduction channel for proprioception. Nat. Neurosci. (18), 1756-1762. Chosen as cover article.
J.A. Franco, H.E. Kloefkorn, S. Hochman, K.A. Wilkinson (2014) An In Vitro Adult Mouse Muscle-nerve Preparation for Studying the Firing Properties of Muscle Afferents. J. Vis. Exp. (91), e51948, doi:10.3791/51948.